Multidisciplinary Approaches to Theory in Medicine

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Ray Paton, Laura McNamara
Elsevier, 2006 - 531 páginas

This volume will be a collection of chapters from authors with wide experience in their research field. The purpose is to produce a coherent book that reflects the common theme of theory in medical thinking and multidisciplinary research practice. In this context "theory" relates to frameworks of concepts, facts, models etc that help to inform practitioners (clinicians, scientists and engineers) both within their own fields and as they seek to share dialogue with colleagues from other fields.

Multidisciplinary Approaches to Theory in Medicine will therefore be integrative across a broad spectrum of fields within medicine. To achieve this the chapters will be associated with others in a number of meaningful ways. Each chapter will share a number of points of contact that will include at least two of the following:

  • Similar biomedical area (e.g., immunity, neuroscience, endocrinology, pathology, oncology, haematology, .)
  • Similar multidisciplinary theoretical contexts (e.g., modelling, analysis, description, visualization, complex systems, .)
  • Similar multidisciplinary medical issues and questions (e.g., clinical practice, decision making, informatics, .)


  • Uniquely explores role of interdisciplinary exchange in the development and expansion of medical theory
  • Timely and insightful essays on the growth and development of medical theories from some of the world's top clinicians and medical researchers, including Werner Arber, Frank Vertosick, and David Weatherall
  • Assembles diverse perspectives on medicine and physiology from biology, statistics, ethics, computer science, philosophy, history
  • Uniquely illuminates the social and historical processes through which theoretical research translates into clinical practice
  • Reveals the growing role of technology, especially computational modelling, in changing the nature of Western medicine

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Contenido

1 Disorders of haemoglobin from phenotype to genotype
1
2 Between bleeding and thrombosis or beyond
15
3 The theory of molecular evolution and its medical implications
31
4 What is a medical theory?
47
5 Medicine as a moral epistemology
63
6 Theory in medical education an oxymoron?
89
7 Knowledge arguments and intentions in clinical decisionmaking
103
8 Analogies conventions and expert systems in medicine some insights from a XIX century physiologist
131
15 Systems biology cell specificity and physiology
265
16 Modelling T cell activation proliferation and homeostasis
281
17 A theory for complex systems reactive animation
309
18 Modelling of haemodynamics in the cardiovascular system by integrating medical imaging techniques and computer modelling tools
325
19 Vasopressin and homeostasis running hard to stay in the same place
353
20 Mathematical modelling of angiogenesis and vascular adaptation1
369
21 Towards understanding the physical basis of reentrant cardiac arrhythmias
389
22 Reflections on the quantitative analysis of liver fibrosis in biopsy specimens
411

9 Reliability of measurements in medical research and clinical practice
147
10 Advanced data mining and predictive modelling at the core of personalised medicine
165
11 Designs and therapies for stochastic neural systems
193
12 Mining scenarios for hepatitis B and C
209
13 Modelling the in vivo growth rate of HIV implications for vaccination
231
14 A flexible iterative approach to physiological modelling
247
23 A network approach to living tissues
431
24 Genetic algorithms in radiotherapy
447
25 Tissue engineering the multidisciplinary epitome of hope and despair
483
Index
525
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