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WARREN G. MAGNUSON, Washington, Chairman JOHN O. PASTORE, Rhode Island

NORRIS COTTON, New Hampshire VANCE HARTKE, Indiana

HUGH SCOTT, Pennsylvania PHILIP A, HART, Michigan

WINSTON PROUTY, Vermont HOWARD W. CANNON, Nevada

JAMES B. PEARSON, Kansas RUSSELL B, LONG, Louisiana

ROBERT P. GRIFFIN, Michigan FRANK E. MOSS, Utah

HOWARD H. BAKER, JR., Tennessee
ERNEST F. HOLLINGS, South Carolina CHARLES E. GOODELL, New York
DANIEL K. INOUYE, Hawaii

MARLOW W. COOK, Kentucky
JOSEPH D. TYDINGS, Maryland
WILLIAM B. SPONG, JR., Virginia

FREDERICK J. LORDAN, Staf Director
MICHAEL PERTSCHUK, Chief Counsel

LEONARD BICKWIT, Jr., Staf Counsel
ARTHUR PANKOPF, Jr., Minority Staff Director

J. PAUL MOLLOY, Minority Staj Counsel

SUBCOMMITTEE ON ENERGY, NATURAL RESOURCES, AND THE ENVIRONMEN'

PHILIP A. HART, Michigan, Chairman

FRANK E. MOSS, Utah, Vice Chairman JOHN O. PASTORE, Rhode Island

HOWARD H. BAKER, JR., Tennessee RUSSELL B. LONG, Louisiana

CHARLES E. GOODELL, New York JOSEPH D. TYDINGS, Maryland

HUGH SCOTT, Pennsylvania WILLIAM B. SPONG, JR., Virginia

MARLOW W. COOK, Kentucky (II)

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and Toxicologic
Clinical Picture and Etiology or mora
Collabotative Bioassay for Chick Edema Factor, article
Cushing, R. L., on behalf of the Hawaiian Sugar Planters' Association,

Honolulu, Hawaii, statement...
Decontamination of Pesticides in Soils, article from Residue Reviews
Defoliants, Deformities: What Risk? 'article.---
Determination of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in 2,4,5-Trichloro-

phenoxyacetic Acid by Gas-Liquid Chromatography, letter of June 22,
1965.

469 384 104

367

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CONTENTS

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Opening statement by the chairman.

CHRONOLOGICAL LIST OF WITNESSES

APRIL 7, 1970

Bayley, Dr., Ned D., director, Science and Education, Department of

Agriculture; accompanied by Dr. T. C. Byerly, assistant director.--.

Letter of January 7, 1970..

Prepared statement..

Kotin, Dr., Paul, director, National Institute of Environmental Health

Sciences
Turner, James, Center for Study of Responsive Law, Washington, D.C..

Letter of April 30, 1970-
Wellford, Harrison, Center for Study of Responsive Law, Washington,
D.C.-

Letter of April 30, 1970-
Westing, Dr. Arthur H., chairman, Biology Department, Windham Col-

lege, Putney, Vt...

APRIL 15, 1970

Epstein, Dr. Samuel S., Children's Cancer Research Foundation, Inc.,

and Harvard Medical School, Boston, Mass.

Appendix I.

Appendix II.

Johnson, Dr. Julius E., vice president and director of research, the Dow

Chemical Co.; accompanied by Etcyl Blair, director Dow Agricultural

Chemical Research, V. K. Rowe, director, Dow Toxicological Laboratory,

and George Lynn, director, Government Regulatory Relations, the

Dow Chemical Co.

Steinfeld, Dr. Jesse, Surgeon General, Department of Health, Education,

and Welfare; accompanied by Dr. David Gaylor, Dr. Diane Courtney,

and Dr. Dale Lindsay--

Verrett, Dr. Jacqueline, Food and Drug Administration, Department of

Health, Education, and Welfare....

ADDITIONAL ARTICLES, LETTERS, AND STATEMENTS

A reporter at large: Defoliation, article from the New York Times ---
Byerly, Dr. T. C., assistant director, Science and Education, Department

of Agriculture, letter of April 21, 1970.--

Chemical and Toxicological Evaluations of Isolated and Synthetic Chloro

Derivatives of Dibenzo-p-dioxin, article from Nature..

Chick Edema Factor, article.

Chick Edema Factor: Some Tissue Distribution Data and Toxicologic

Effects in the Rat and Chick, article.-

Clinical Picture and Etiology of Chloracne, article--

Collabotative Bioassay for Chick Edema Factor, article--

Cushing, R. L., on behalf of the Hawaiian Sugar Planters’ Association,

Honolulu, Hawaii, statement.--

Decontamination of Pesticides in Soils, article from Residue Reviews.
Defoliants, Deformities: What Risk? article---
Determination of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in 2,4,5-Trichloro-
phenoxyacetic Acid by Gas-Liquid Chromatography, letter of June 22,
1965.

107

467

469

384
104

367

12

57

330

278

328

467

314

17

2

128
466

DuBridge, Dr. Lee A., Director, Office of Science and Technology, Depart-

ment of Health, Education, and Welfare, statement.--

Effect and Persistence of Herbicides Applied to Soil in Puerto Rican Forests,

article from Weed Science..

Electron Microscopic Alterations in the Liver of Chicken Fed Toxic Fat,

article.

Growth of Crops in Soils After Herbicidal Treatments for Brush Control in

the Tropics, article from Agronomy Journal...

Hays, Harry W., Ph. D., Director, Agricultural Research Service, Pesticides

Regulation Division, U.S. Department of Agriculture, letter of Novem-

ber 6, 1966

Herbicides in Soils, article from Agricultural Research Service-
Identification and Crystal Structure of a Hydropericardium-Producing

Factor: 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin, article from Acta Crys-

tallographica
Injection of Chemicals Into the Yolk Sac of Fertile Eggs Prior to Incuba-

tion as a Toxicity Test, article from Toxicology and Applied Pharma-

cology-
Internal Preliminary Report Analysis of Commercial Chlorophenols for

Trace Amounts of Their Condensation and Polymerization Products,

article...
Lawrence, J. F., Brig. Gen., U.S. Marine Corps, Deputy Assistant to the
Secretary for Legislative Affairs, Office of the Secretary of Defense, letter

of April 21, 1970..
Light and Electron Microscopic Observations in Macaca mulatta Monkeys

Fed Toxic Fat, article--

Lipson, Dr. Steven, chief, Division of Epidemiology and Surveillance,

Montgomery County Health Department, letter of March 17, 1970.--
McCarthy, Hon. Richard D., U.S. Representative from New York, state-

ment...

Probe Into Use of Herbicide, hearings -
Metcalf, Hon. Lee, U.S. Senator from Montana, statement-
Note on an Improved Cleanup Method for the Detection of Chick Edema

Factor in Fats and Fatty Acids by Electron Capture Gas Chromatog-
raphy, article..
Nutritional Adjuncts, Chick Edema Factor. III. Application of Micro-

coniometric Gas Chromatography to Detection of Chick Edema Factor

in Fats or Fatty Acids, article -
Occupational Intoxication Occurring in the Production of Chlorophenol

Compounds, article..
Occurrence of the Chick Pericardial Edema Factor in Some Oleic Acids

and Products Derived Therefrom, article. -

Persistence of 2,4-D, 2,4,5,5-T, and Dicamba in Range Forage Grasses,

article from Weeds.

Pierovich, John M., assistant regional forester, Albuquerque, N. Mex.,

letter of February 26, 1970--

Progress in the Chick Edema Problem, article..

Report on Methodology for Chlorinated Aromatics in Fats, Oils, and

Fatty Acids, article.

Response of Rabbit Skin to Compounds Reported to Have Caused Acne-

form Dermatitis, article-

Role of "Toxic Fat” in the Production of Hydropericandium and Ascites

in Chickens, article..

Ryan, M. J., acting director, Office of Legislative Services, Department of

Health, Education, and Welfare, letter of March 12, 1970-
Soil Persistence of 2,4,5-T, article from Chemical Fallout.
Steinfeld, Dr. Jesse L., Surgeon General, Department of Health, Education,

and Welfare, letter of January 21, 1970-

Studies of the Chick Edema Disease, article from Poultry Science..

Studies of the Chick Edema Factor. II. Isolation of a Toxic Substance,

article....

Studies of the Chicken Edema Disease Factor, article from the Journal of

the Association of Official Agricultural Chemists-
Studies on the Metabolism of Chick Edema Factor: Distribution in Chick

Tissues, article.-
Technic for Testing Acnegenic Potency in Rabbits, Applied to the Potent

Acnegen, 2,3,7,8-Tetrachlorodibenzo-p-Dioxin, article.

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