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CONTENTS

Kotin, Dr., Paul, director, National Institute of Environmental Health

Sciences

Turner, James, Center for Study of Responsive Law, Washington, D.C..
Letter of April 30, 1970_-

Page

18

468

Wellford, Harrison, Center for Study of Responsive Law, Washington,
D.C...

6

Letter of April 30, 1970.

468

Westing, Dr. Arthur H., chairman, Biology Department, Windham Col-
lege, Putney, Vt___

76

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ADDITIONAL ARTICLES, LETTERS, AND STATEMENTS

A reporter at large: Defoliation, article from the New York Times____
Byerly, Dr. T. C., assistant director, Science and Education, Department
of Agriculture, letter of April 21, 1970---

107

467

Decontamination of Pesticides in Soils, article from Residue Reviews
Defoliants, Deformities: What Risk? article___.

384

104

Determination of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in 2,4,5-Trichloro-
phenoxyacetic Acid by Gas-Liquid Chromatography, letter of June 22,

1965

367

Electron Microscopic Alterations in the Liver of Chicken Fed Toxic Fat,
article...

303

Growth of Crops in Soils After Herbicidal Treatments for Brush Control in
the Tropics, article from Agronomy Journal_

45

Hays, Harry W., Ph. D., Director, Agricultural Research Service, Pesticides

Regulation Division, U.S. Department of Agriculture, letter of Novem-

ber 6, 1966__

Herbicides in Soils, article from Agricultural Research Service
Identification and Crystal Structure of a Hydropericardium-Producing
Factor: 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin, article from Acta Crys-
tallographica

Injection of Chemicals Into the Yolk Sac of Fertile Eggs Prior to Incuba-
tion as a Toxicity Test, article from Toxicology and Applied Pharma-
cology-
Internal Preliminary Report Analysis of Commercial Chlorophenols for
Trace Amounts of Their Condensation and Polymerization Products,
article...

Lawrence, J. F., Brig. Gen., U.S. Marine Corps, Deputy Assistant to the
Secretary for Legislative Affairs, Office of the Secretary of Defense, letter
of April 21, 1970.

Light and Electron Microscopic Observations in Macaca mulatta Monkeys
Fed Toxic Fat, article...

Lipson, Dr. Steven, chief, Division of Epidemiology and Surveillance,
Montgomery County Health Department, letter of March 17, 1970-

McCarthy, Hon. Richard D., U.S. Representative from New York, state-

ment..

Probe Into Use of Herbicide, hearings.

Metcalf, Hon. Lee, U.S. Senator from Montana, statement-

Note on an Improved Cleanup Method for the Detection of Chick Edema
Factor in Fats and Fatty Acids by Electron Capture Gas Chromatog-
raphy, article.

Nutritional Adjuncts, Chick Edema Factor. III. Application of Micro-
coniometric Gas Chromatography to Detection of Chick Edema Factor
in Fats or Fatty Acids, article___

Occupational Intoxication Occurring in the Production of Chlorophenol
Compounds, article....

Occurrence of the Chick Pericardial Edema Factor in Some Oleic Acids
and Products Derived Therefrom, article.

57

330

278

328

467

314

17

466

321

265

241

219

Ryan, M. J., acting director, Office of Legislative Services, Department of
Health, Education, and Welfare, letter of March 12, 1970.
Soil Persistence of 2,4,5-T, article from Chemical Fallout.

126

41

Steinfeld, Dr. Jesse L., Surgeon General, Department of Health, Education,

and Welfare, letter of January 21, 1970_.

38

Studies of the Chicken Edema Disease Factor, article from the Journal of
the Association of Official Agricultural Chemists_

207

Studies on the Metabolism of Chick Edema Factor: Distribution in Chick
Tissues, article___

311

Technic for Testing Acnegenic Potency in Rabbits, Applied to the Potent
Acnegen, 2,3,7,8-Tetrachlorodibenzo-p-Dioxin, article..

249

Teratogenic Evaluation of 2,4,5-T, article.

U.S. Shows Signs of Concern Over Effect in Vietnam of 9-year Defoliation
Program, article from New York Times -

Use of the Chicken Embryo in the Assay of Aflatoxin Toxicity, article
from the Journal of the Association of Official Agricultural Chemists...
Whiteside, Thomas, Department of Amplification, letter of March 5, 1970_

98

102

290

123

EFFECTS OF 2,4,5-T ON MAN AND THE

ENVIRONMENT

TUESDAY, APRIL 7, 1970

U.S. SENATE,

COMMITTEE ON COMMERCE,

SUBCOMMITTEE ON ENERGY, NATURAL RESOURCES,

AND THE ENVIRONMENT,

Washington, D.C. The subcommittee met, pursuant to notice, at 10 a.m., in room. 1318, New Senate Office Building, Hon. Philip A. Hart, presiding. Present: Senators Hart, Inouye, and Baker.

OPENING STATEMENT BY THE CHAIRMAN

Senator HART. The committee will be in order.

Permit me a brief opening statement. For the Subcommittee on Energy, Natural Resources, and the Environment, I welcome those present for the first of these 2 days of hearings we are holding to examine the effect of the herbicide known as 2,4,5-T on man and the environment. I suggest that what is at stake at these hearings is virtually impossible to evaluate at this moment, in light of the uncertainty about this frequently used pesticide.

The questions which have been raised recently concerning the hazards of 2,4,5,-T and related chemicals may in the end appear to be much ado about very little indeed.

On the other hand, they may ultimately be regarded as portending the most horrible tragedy ever known to mankind.

What does emerge clearly from this uncertainty is that we must take steps to eliminate it. In view of the potential disaster that could befall us or conceivably has insidiously already befallen us -absolutely no delay is tolerable in the search for answers to the questions posed.

It is with the hope that Congress will be able to play an active role in that search that these hearings have been scheduled.

Although the title of the hearing refers to the effects of 2,4,5,-T alone, it should be made clear early in the game that other similar chemicals may give rise to similar problems for the environment.

Witnesses should feel free, therefore, to address themselves to any such chemical to the extent that it bears upon the central problems

at issue.

Our first witness was to have been Congressman Richard McCarthy, of New York, but unfortunately he will not be able to be Staff member assigned to this hearing: Leonard Bickwit, Jr.

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