TC Publication, Tema 345U.S. Government Printing Office, 1970 |
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Página 23
... fermentation . These deficiencies are summarized as follows : 1 . 2 . 3 . 4 . 5 . Penicillin G is split by acids and is therefore inacti- vated by gastric juices ; it is consequently most effec- tive when given by injection , although ...
... fermentation . These deficiencies are summarized as follows : 1 . 2 . 3 . 4 . 5 . Penicillin G is split by acids and is therefore inacti- vated by gastric juices ; it is consequently most effec- tive when given by injection , although ...
Página 24
... fermentation process using various species of the penicillium mold ; chemically , they are all derivatives of 6 - amino- penicillanic acid ( hereafter referred to as 6 - APA ) . Penicillin G ( or benzylpenicillin ) was the principal ...
... fermentation process using various species of the penicillium mold ; chemically , they are all derivatives of 6 - amino- penicillanic acid ( hereafter referred to as 6 - APA ) . Penicillin G ( or benzylpenicillin ) was the principal ...
Página 25
... fermentation process and still remains the most widely used of all the penicillins . In order to increase the yield of penicillin G and eliminate unwanted side products , the standard commercial practice is to add a suitable pre- cursor ...
... fermentation process and still remains the most widely used of all the penicillins . In order to increase the yield of penicillin G and eliminate unwanted side products , the standard commercial practice is to add a suitable pre- cursor ...
Página 48
... fermentation processes s consistently of one configuration ; such 6 - aminopenicil lanic acid is presently used in the production of the com- pounds of this invention . The products of the present invention are prepared by reaction of 6 ...
... fermentation processes s consistently of one configuration ; such 6 - aminopenicil lanic acid is presently used in the production of the com- pounds of this invention . The products of the present invention are prepared by reaction of 6 ...
Página 50
... fermentation broths or aque- ous solutions of crude 6 - aminopenicillarie acid , use can be made of organic solvents which do not contain reactive hydrogen atoma . Examples of such iner solvents are dimethylformamide , dimethylacetamide ...
... fermentation broths or aque- ous solutions of crude 6 - aminopenicillarie acid , use can be made of organic solvents which do not contain reactive hydrogen atoma . Examples of such iner solvents are dimethylformamide , dimethylacetamide ...
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Términos y frases comunes
6-amino 6-aminopenicillanic acid acetone acylating added addition alleged American Home Products amine ampicillin antibiotic antitrust suit aqueous phase aqueous solution assaying Ayerst barium carbonate Beech-Nut Beecham Group Limited benzylpenicillin Bristol Laboratories Bristol-Myers Company butanol Canada carbonate carboxylic acid catalyst chemical chlorocarbonate cillin Clemm complainants Court Department of Justice E. R. Squibb Example fermentation filed filtered free acid Furazolidone Gram-negative Home Products Corporation hydrochloric acid hydrogen hydrogen at room importer of ampicillin investigation Jersey licensees manufacture method of competition million in 1968 mixture obtained Order be issued patent misuse penicillanic acid penicillin percent pharmaceutical phenylacetic acid plant PREPARATION President reaction respondent room temperature sales of ampicillin section 337 proceeding sell ampicillin semi-synthetic penicillins sodium bicarbonate sodium hydroxide sodium salt solvent Squibb and Sons stirred subsidiary Tariff Commission Temporary Exclusion Order tion triethylamine unfair act unfair method United vacuo Virgin Islands washed with water Wyeth Zenith Laboratories